Status:
UNKNOWN
Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants
Lead Sponsor:
Oxford University Hospitals NHS Trust
Conditions:
Leukemia
Myelodysplastic Syndromes
Eligibility:
All Genders
18+ years
Brief Summary
RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients at risk of developing myelodysplastic syndrome may help doctors learn more about changes that occur in DNA and iden...
Detailed Description
OBJECTIVES: Primary * To identify novel biomarkers of disease that would help in the initial diagnosis of myelodysplastic syndromes (MDS). Secondary * To understand the genesis of anemia in cancer...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Must meet 1 of the following criteria:
- Being investigated for a potential blood disorder due to abnormal blood count
- Patients with a known blood disorder who are having a bone marrow sample taken as part of the assessment of that disorder
- Patients undergoing hip replacement surgery at Nuffield Orthopaedic Centre, Oxford meeting the following criteria:
- Not on treatment likely to impair bone marrow function
- No history of having had treatment likely to have impaired bone marrow function
- Normal blood count
- Archived samples from patients with known blood disorder
- PATIENT CHARACTERISTICS:
- See Disease Characteristics
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
January 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00899327
Start Date
January 1 2007
Last Update
July 8 2009
Active Locations (1)
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1
Oxford Radcliffe Hospital
Oxford, England, United Kingdom, 0X3 9DU