Status:
COMPLETED
DNA Analysis of Tissue From Patients With T-Cell Acute Lymphoblastic Leukemia
Lead Sponsor:
ECOG-ACRIN Cancer Research Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
18-120 years
Brief Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This ...
Detailed Description
OBJECTIVES: * Identify the transcriptional signatures associated with the presence of NOTCH1 mutations in primary T-cell acute lymphoblastic leukemia (T-ALL) cells using oligonucleotide microarrays. ...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Confirmed diagnosis of T-cell acute lymphoblastic leukemia
- Frozen lymphoblast samples available
- NOTCH1-mutated or wild type sample available
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
- Exclusion Criteria:
- Not applicable
Exclusion
Key Trial Info
Start Date :
December 28 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 30 2009
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT00899366
Start Date
December 28 2006
End Date
July 30 2009
Last Update
February 5 2020
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