Status:
COMPLETED
Proteases in Patients With Prostate Cancer That Has Spread to the Bone
Lead Sponsor:
Barbara Ann Karmanos Cancer Institute
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Anemia
Metastatic Cancer
Eligibility:
MALE
40+ years
Brief Summary
RATIONALE: Collecting and storing samples of bone marrow and tissue from patients to test in the laboratory may help the study of cancer. PURPOSE: This laboratory study is comparing proteases (enzyme...
Detailed Description
OBJECTIVES: * Examine the roles of proteases and protease-associated molecules in bone metastases in patients with metastatic prostate cancer. OUTLINE: Patients undergo bone marrow aspiration and co...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Meets 1 of the following criteria:
- Diagnosis of metastatic prostate cancer
- Patients with documented bone metastases on radiologic imaging studies must undergo bone marrow biopsy
- Male patients ≥ 50 years of age without cancer who are scheduled to undergo bone biopsy for other clinically indicated reasons, including any of the following:
- Myelodysplasia
- Anemia
- Monoclonal gammopathy of undetermined significance
- Male or female patients ≥ 40 years of age without metastatic bone cancer who are scheduled to undergo an orthopedic procedure involving removal of bone specimen
- PATIENT CHARACTERISTICS:
- See Disease Characteristics
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
July 1 2001
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2008
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT00899665
Start Date
July 1 2001
End Date
January 1 2008
Last Update
February 11 2014
Active Locations (1)
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1
Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, United States, 48076