Status:

UNKNOWN

Pharmacokinetics of Dactinomycin in Young Patients With Cancer

Lead Sponsor:

Children's Cancer and Leukaemia Group

Conditions:

Unspecified Childhood Solid Tumor, Protocol Specific

Eligibility:

All Genders

Up to 21 years

Brief Summary

RATIONALE: Studying samples of blood in the laboratory from patients with cancer receiving dactinomycin may help doctors learn how dactinomycin works in the body and how patients will respond to treat...

Detailed Description

OBJECTIVES: * Determine the pharmacokinetics (PKs) of dactinomycin in pediatric patients with cancer. * Determine the degree of interpatient variation in the PKs of this drug. * Determine the influen...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of cancer
  • Currently being treated with dactinomycin on a clinical trial at a United Kingdom Children's Cancer Study Group center
  • PATIENT CHARACTERISTICS:
  • Single- or double-lumen central venous catheter or portacath in place
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    June 1 2006

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    Estimated Enrollment :

    50 Patients enrolled

    Trial Details

    Trial ID

    NCT00900354

    Start Date

    June 1 2006

    Last Update

    August 12 2013

    Active Locations (22)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 6 (22 locations)

    1

    Our Lady's Hospital for Sick Children Crumlin

    Dublin, Ireland, 12

    2

    Birmingham Children's Hospital

    Birmingham, England, United Kingdom, B4 6NH

    3

    Institute of Child Health at University of Bristol

    Bristol, England, United Kingdom, BS2 8AE

    4

    Addenbrooke's Hospital

    Cambridge, England, United Kingdom, CB2 2QQ