Status:
COMPLETED
Effect of Systemic Ropivacaine on Hyperalgesia, Flare Reaction and Peripheral Nerve Excitability
Lead Sponsor:
University of Zurich
Conditions:
Healthy Volunteers
Eligibility:
MALE
18-65 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the effect of intravenous ropivacaine and lidocaine on the receptive field of primary sensory afferents and their influence on the vascular bed. \*Trial with m...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Male
- Age: 18 - 65 years
- Weight: 50-100kg
- Height: 155-195cm
- Signed and dated informed consent
- Sufficient command of German language
- Exclusion criteria:
- Contraindications to the class of drugs under study
- Vulnerable subjects (intellectually or mental impaired)
- Known hypersensitivity to class of drugs or the investigational product
- Drug abuse
- Known peripheral neuropathies
- Diabetes mellitus
- Chronic alcohol consumption
- Congestive heart disease
- Participants of other studies during study period
- Smoker
Exclusion
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2011
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00900913
Start Date
January 1 2010
End Date
July 1 2011
Last Update
August 8 2011
Active Locations (1)
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1
Clinical Trial Center
Zurich, Switzerland