Status:
TERMINATED
Thromboelastography (TEG®) and Platelet Function in Patients on Anti-platelet Agents
Lead Sponsor:
McMaster University
Collaborating Sponsors:
University Health Network, Toronto
Hamilton Health Sciences Corporation
Conditions:
Blood Clotting
Eligibility:
All Genders
40-85 years
Brief Summary
Can a post-operative analysis using a simple blood test (Thromboelastography(TEG®)) and Platelet Mapping Assay (PMA™) be able to detect the occurence of clotting or bleeding complications in patients ...
Detailed Description
Two hundred patients coming for surgery who are taking anti-platelet medications will be enrolled in this study as a pilot, to determine the feasibility for a larger study. A simple blood test for clo...
Eligibility Criteria
Inclusion
- patients on aspirin and/or clopidogrel for at least 10 days, having non-ambulatory, non-cardiac, elective surgery
Exclusion
- anemia (Hb \< 100) or thrombocytopenia (platelet count \< 80), having any known clotting abnormalities
- family history of clotting abnormalities
- concurrently on NSAIDs, warfarin therapy or other treatments affecting platelet function
- renal impairment (Cr \> 110 mg for females or Cr \> 125 mg) or INR \> 1.2
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00901160
Start Date
January 1 2008
End Date
June 1 2011
Last Update
April 8 2015
Active Locations (2)
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1
Hamilton Health Sciences
Hamilton, Ontario, Canada, L8L 2X2
2
University Health Network
Toronto, Ontario, Canada, M5G 2C4