Status:
COMPLETED
Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload
Lead Sponsor:
Elliott Vichinsky
Conditions:
Thalassemia
Iron Overload
Eligibility:
All Genders
8+ years
Phase:
PHASE2
Brief Summary
This is a pilot study looking at the safety and efficacy of giving combination chelation with deferasirox and deferoxamine. The hypothesis is that combination chelation is safe in decreasing overall i...
Detailed Description
This was a phase two pilot clinical trial designed to evaluate the safety and efficacy of the combination of deferasirox and deferoxamine in transfusion dependent thalassemia with a range of systemic ...
Eligibility Criteria
Inclusion
- Transfusion Dependent Thalassemia
- If iron between 5-15 mg/g dry liver by SQUID, subject must have a documented endocrinopathy or cardiac finding
- Older than 8 years
Exclusion
- Participating on another interventional clinical trial
Key Trial Info
Start Date :
September 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2012
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00901199
Start Date
September 1 2007
End Date
October 1 2012
Last Update
August 12 2021
Active Locations (1)
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1
CHRCO
Oakland, California, United States, 94609