Status:
COMPLETED
Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Autism Speaks
Conditions:
Autistic Disorder
Autism Spectrum Disorder
Eligibility:
All Genders
16-45 years
Phase:
NA
Brief Summary
This study will investigate and contrast the effects of two psychological treatments for adults with autism spectrum disorder. Cognitive Enhancement Therapy (CET) is a cognitive remediation interventi...
Detailed Description
Autism spectrum disorder (ASD) is characterized by marked impairments in social and non-social cognitive ability that persist well into adulthood and contribute to significant functional disability. T...
Eligibility Criteria
Inclusion
- Age 16-45 years
- Diagnosis of autism, Asperger's syndrome, or pervasive developmental disorder not otherwise specified (NOS) verified by the autism diagnostic observation schedule (ADOS) or autism diagnostic interview-revised (ADI-R)
- Presence of significant social and cognitive disability, based on the Cognitive Style and Social Cognition Eligibility Interview (Hogarty et al., 2004)
- Intelligence quotient (IQ) greater than 80
- Ability to read and speak fluent English
- Availability of a family member or close friend allowed to provide information on the participant
- Ability to attend weekly treatment sessions in Pittsburgh, PA
Exclusion
- Organic brain syndrome
- IQ \< 80
- English language skills below a sixth grade level
- Persistent suicidal or homicidal behavior
- History of substance abuse or dependence within the past 3 months
- Comorbid attention deficit hyperactivity disorder (ADHD)
- Comorbid personality disorder
- History of disruptive or violent behavior
- Any magnetic resonance imaging contraindications
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT00902798
Start Date
August 1 2010
End Date
June 1 2017
Last Update
April 13 2020
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213