Status:
COMPLETED
Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia
Lead Sponsor:
Beth Israel Deaconess Medical Center
Collaborating Sponsors:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions:
Aphasia
Stroke
Eligibility:
All Genders
21-80 years
Phase:
PHASE3
Brief Summary
We are doing this clinical trial in order to evaluate two different treatments for non-fluent aphasia: Melodic Intonation Therapy (MIT) and Speech Repetition Therapy (SRT). MIT uses a simple form of s...
Detailed Description
One of the few accepted treatments for severe non-fluent aphasia is Melodic Intonation Therapy (MIT). Inspired by the common clinical observation that patients can actually sing the lyrics of a song b...
Eligibility Criteria
Inclusion
- 21-80 years of age
- first-time ischemic left-hemispheric stroke or cerebrovascular accident
- at least 12 months out from first ischemic stroke
- right-handed (prior to stroke)
- diagnosis of non-fluent or dysfluent aphasia
Exclusion
- older than 80 years of age
- more than 1 stroke
- presence of metal or metallic or electronic devices that cannot be exposed to the MRI environment
- a terminal medical condition; history of major neurological or psychiatric diseases (e.g. epilepsy; meningitis, encephalitis)
- use of psychoactive drugs/medications such as antidepressants, antipsychotic, stimulants
- active participation in other stroke recovery trials testing experimental interventions
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00903266
Start Date
February 1 2008
End Date
June 1 2020
Last Update
September 21 2020
Active Locations (1)
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1
Beth Israel Deaconess Medical Center / Harvard Medical School
Boston, Massachusetts, United States, 02215