Status:

COMPLETED

Binge Eating and Chromium Study

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

National Alliance for Research on Schizophrenia and Depression

Conditions:

Binge Eating Disorder

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to test the feasibility and preliminary efficacy of a 6-month chromium picolinate (CrPic) treatment trial in binge eating disorder (BED).

Detailed Description

Binge eating (i.e., the consumption of unusually large amounts of food with a sense of loss of control) is a common problem with serious public health implications in large part due to its role in obe...

Eligibility Criteria

Inclusion

  • Currently meets DSM-IV criteria for binge eating disorder (BED);
  • Is able to provide informed consent and meet study visit requirements; and
  • Is psychiatrically stable (e.g., no current suicidal or homicidal intent or other psychiatric condition that requires acute intervention).

Exclusion

  • Body mass index (BMI) \< 24.9 kg/m\^2 (underweight or normal weight) or ≥ 40 kg/m\^2 (severely obese);
  • Postmenopausal;
  • Age \< 18 or \> 55 years;
  • Pregnant, planning on becoming pregnant during the study period, or lactating;
  • Current psychotropic medication use;
  • Current use of insulin or other medications to control glucose metabolism;
  • Current use of medications known to significantly influence appetite or weight \[i.e., over-the-counter appetite suppressants that contain phentermine or sibutramine, atypical antipsychotic agents with high weight gain liability (such as olanzapine, risperidone, etc), prednisone, etc.\];
  • Fasting glucose level \> 126 mg/dL (indicative of diabetes); and
  • Creatinine level indicating renal insufficiency (\> 1.0 for women; \> 1.2 for men).

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT00904306

Start Date

July 1 2008

End Date

July 1 2011

Last Update

April 3 2012

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