Status:
COMPLETED
The Stockholm III Trial on Different Preoperative Radiotherapy Regimens in Rectal Cancer
Lead Sponsor:
Karolinska Institutet
Collaborating Sponsors:
Swedish Cancer Society
The Swedish Research Council
Conditions:
Rectal Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Preoperative radiotherapy (RT) is recommended to many patients with localised rectal cancer, not previously treated with pelvic RT. However, the optimum fractionation, the timing of surgery and the be...
Detailed Description
840 participants (men and women) with a biopsy verified adenocarcinoma of the rectum scheduled for an open abdominal procedure were enrolled at 18 Swedish Hospitals during 1998-2013. In the initial p...
Eligibility Criteria
Inclusion
- Biopsy confirmed clinically resectable rectal adenocarcinoma within 15 cm from the anal verge
- Planned for bowel resection with an abdominal procedure.
- Informed consent.
Exclusion
- Distant metastases
- Locally advanced unresectable tumors
- Planned for local excision
- Previous radiotherapy to the abdominal or pelvic region
- Severe ischemic heart disease or symptoms of severe arteriosclerosis
Key Trial Info
Start Date :
November 1 1998
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2018
Estimated Enrollment :
840 Patients enrolled
Trial Details
Trial ID
NCT00904813
Start Date
November 1 1998
End Date
March 31 2018
Last Update
May 7 2021
Active Locations (18)
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1
Mora Hospital
Mora, Dalarna County, Sweden
2
Danderyds Hospital
Danderyd, Stockholm County, Sweden
3
Norrtälje Hospital
Norrtälje, Stockholm County, Sweden
4
Södertälje Hospital
Södertälje, Stockholm County, Sweden