Status:
COMPLETED
The Effect of Different Dosages of Solute Clearance on Outcome in Twice Weekly Hemodialysis Patients
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Renal Replacement Therapy
Hemodialysis
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Adequacy of solute clearance makes a profound impact on clinical outcome in maintenance hemodialysis patients. Thus far, guidelines on the target of solute clearance (Kt/V or URR) are based on patient...
Detailed Description
This is a prospective, randomized, multi-center intervention study. 400 maintenance hemodialysis patients with twice dialysis sessions per week will be enrolled into the study. All the patients have t...
Eligibility Criteria
Inclusion
- Patients undergoing maintenance hemodialysis for more than 12 weeks were included in the study.
- The patients have their dialysis sessions twice weekly and have baseline Kt/V between 1.2 and 1.7 (1.2 ≤ Kt/V \< 1.7).
- Age from 18 to 80, male or female.
- Patients have long term vascular access.
Exclusion
- Patients with an expected survival less than 12 months.
- Without informed consent.
- Unstable organ disease such as uncurable cancer,active inflammation disease and mental disease.
- Patients with an expected follow up less than 48 weeks,such as planned kidney transplant.
- Other conditions regarded as unsuitability by investigator, such as pregnancy, alcohol or drug indulgence. A dry weight more than 90 kg is also excluded in the study.
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT00906555
Start Date
June 1 2009
End Date
June 1 2012
Last Update
October 13 2016
Active Locations (1)
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1
Renji Hospital, Shanghai Jiao Tong University school of medicine
Shanghai, China, 200001