Status:
COMPLETED
Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)
Lead Sponsor:
Johann Wolfgang Goethe University Hospital
Conditions:
Dyspnea
Eligibility:
All Genders
7-30 years
Brief Summary
Vocal cord dysfunction is a rare clinical picture. It is labeled as a sudden and threatening dyspnea. Patients with VCD may also present cough, hoarseness, wheezing, and chest tightness, but an inspir...
Detailed Description
VCD appears to be significantly more common among females. The episode of dyspnea underlies the paradoxical, intermittent adduction of the vocal cords during inspiration. Methacholine challenge testin...
Eligibility Criteria
Inclusion
- Informed consent
- Age 7 to 30 Years
- Documented VCD or strong suspicion of VCD
- Pulmonary function test: FEV1 (% pred.) ≥ 70%
Exclusion
- Age \< 7 and \> 30 Years
- Pulmonary function test: FEV1 (% pred.) \< 70%
- Others chronic diseases or infections (e.g., HIV, tuberculosis, malignancy)
- Pregnancy
- Documented alcohol, substance, and/or drug abuse
- Incapability to perform all study procedure
- Current participation in another clinical trial
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT00906867
Start Date
April 1 2009
End Date
March 1 2010
Last Update
March 3 2017
Active Locations (1)
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1
Goethe University Hospital
Frankfurt am Main, Hesse, Germany, 60596