Status:

COMPLETED

Evaluation of [18F]-FMISO for Non Operated Glioblastoma

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Glioblastoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Hypoxia is recognized to be an independent predictor of clinical outcome in oncology. PET using \[18F\]-FMISO has been described to be useful for the non invasive assessment of hypoxia in cancer. The ...

Detailed Description

Hypoxia is one of the worst prognostic factors of clinical outcome in glioblastomas. Today, it is well admitted that hypoxia is heterogeneous, variable within different tumour types and varied spatial...

Eligibility Criteria

Inclusion

  • Patients over 18
  • Patients with a malignant tumour glioblastomas proposed for a radical treatment consisting in conformational radiotherapy and/or chemotherapy
  • Signed informed consent

Exclusion

  • Patients who can't undergo radiotherapy or chemotherapy
  • Patients with distant metastases known before inclusion except renal cancer where patients with metastases can be included
  • Patients suffering of a second cancer or treated before by radiotherapy in the tumour site.
  • Pregnant and breast feeding women, women in age to procreate without contraception

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2013

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT00906893

Start Date

June 1 2009

End Date

January 1 2013

Last Update

February 28 2013

Active Locations (1)

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CHU de Bordeaux - Hôpital Pellegrin

Bordeaux, France, 33076