Status:

TERMINATED

Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers

Lead Sponsor:

Case Comprehensive Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Breast Cancer

Cognitive/Functional Effects

Eligibility:

FEMALE

18+ years

Brief Summary

RATIONALE: Gathering information over time from women undergoing chemotherapy for breast cancer may help doctors learn more about mental and physical fatigue caused by treatment. PURPOSE: This clinic...

Detailed Description

OBJECTIVES: * To assess treatment-related fatigue, cognitive dysfunction, and recovery in women undergoing adjuvant chemotherapy for stage I-III breast cancer as compared with a patient-selected cont...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Meets either of the following criteria:
  • Has completed surgery for stage I-III breast cancer AND meets the following criteria:
  • No bilateral axillary dissection
  • Clinically free of active disease
  • Planning to receive adjuvant chemotherapy for operable breast cancer
  • Friend or relative of patient matched for age (± 10 years) (control)
  • Hormone receptor status not specified
  • PATIENT CHARACTERISTICS:
  • Known menopausal status
  • Able to read English
  • No history of significant cardiovascular disease or stroke, polyneuropathy, amyotrophy, myosthenic syndrome, or pulmonary compromise
  • Prior depression allowed provided that it was not significant
  • Willing to come to the Cleveland Clinic for 3 assessments
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    July 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2010

    Estimated Enrollment :

    18 Patients enrolled

    Trial Details

    Trial ID

    NCT00909662

    Start Date

    July 1 2008

    End Date

    December 1 2010

    Last Update

    October 2 2015

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, United States, 44106-5065

    2

    Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

    Cleveland, Ohio, United States, 44195