Status:

UNKNOWN

Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation

Lead Sponsor:

Post Graduate Institute of Medical Education and Research, Chandigarh

Conditions:

Respiration, Artificial

Ventilator Weaning

Eligibility:

All Genders

10-70 years

Phase:

NA

Brief Summary

This study is a comparison of two most commonly used modes of weaning and the outcomes in the two groups.

Detailed Description

Patients ventilated for more than 24 hours are randomized into two groups - one group of patients undergo gradual reduction of pressure support and in the other, T tube trials are used for weaning. Th...

Eligibility Criteria

Inclusion

  • Mechanically ventilated patients for more than 24 hours
  • Satisfies weaning criteria
  • RSBI \< 80
  • Ratio of PaO2/FiO2 \> 250
  • Arterial partial pressure of oxygen more than 60 mm Hg and carbon dioxide less than 50 mm Hg

Exclusion

  • Systolic blood pressure of less than 100
  • Arterial partial pressure of oxygen less than 60 mm Hg
  • Poor sensorium

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2009

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00911378

Start Date

April 1 2008

End Date

September 1 2009

Last Update

June 22 2009

Active Locations (1)

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Postgraduate Institute of Medical Education and Research

Chandigarh, Chandigarh, India, 160012