Status:
COMPLETED
Does APOE-e4 Predict Delirium and Cognitive Dysfunction After Surgery?
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborating Sponsors:
Canadian Anesthesiologists' Society
University of Ottawa
Conditions:
Delirium
Postoperative Cognitive Dysfunction
Eligibility:
All Genders
60+ years
Brief Summary
Patients with the APOE-ε4 genotype are at increased risk of both vascular dementia and peripheral vascular disease. Patients undergoing major vascular surgery are at particularly high risk of delirium...
Eligibility Criteria
Inclusion
- Age 60 or greater
- Open repair of the abdominal aorta
Exclusion
- refusal;
- planned endovascular repair;
- emergency surgery;
- previous diagnosis of dementia, Parkinson's disease, or psychiatric illness;
- active alcohol or substance abuse; and
- physical inability to complete neuropsychometric testing.
Key Trial Info
Start Date :
August 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00911677
Start Date
August 1 2005
End Date
May 1 2009
Last Update
June 2 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Ottawa Hospital - Civic Campus
Ottawa, Ontario, Canada, K1Y 4E9