Status:
COMPLETED
Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria?
Lead Sponsor:
Institut de Recherche pour le Developpement
Collaborating Sponsors:
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Conditions:
Malaria
Eligibility:
All Genders
5-15 years
Brief Summary
The investigators performed a prospective study, in order to assess the feasibility and safety of restricting antimalarials to rapid diagnostic test (RDT)-confirmed cases in children aged 5 to 15 year...
Detailed Description
This study was designed to measure the incidence of malaria attacks during a 2-week follow-up period in 2 populations of patients. First, an index group (IG, exposed to fever) constituted by schoolchi...
Eligibility Criteria
Inclusion
- Inclusion Criteria in the index group:
- School children aged 5 to 15 years.
- Tympanic temperature at 37.8°C or above, or if a history of fever in the preceding 24 hours was reported.
- A negative malaria (Paracheck® Plasmodium falciparum) RDT.
- Informed consent.
- Asymptomatic children were screened for the Control Group on gender, age, week of inclusion. The first child with a negative RDT and for whom an informed consent was obtained, was included in the CG.
- Exclusion Criteria:
- Adequate malaria treatment within a month prior screening.
Exclusion
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
484 Patients enrolled
Trial Details
Trial ID
NCT00913146
Start Date
February 1 2008
End Date
March 1 2009
Last Update
June 4 2009
Active Locations (1)
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1
Centre de Santé de Commune
Allada, Benin