Status:
TERMINATED
Chronic Subdural Hematoma - Reduction of Recurrence by Treatment With Angiotensin Converting Enzyme Inhibitors
Lead Sponsor:
Odense University Hospital
Collaborating Sponsors:
Alice Brenaa Foundation
The Hede Nielsen Family Foundation
Conditions:
Hematoma, Subdural, Chronic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The project aims at investigating if treatment with the Angiotensin Converting Enzyme inhibitor Coversyl (perindopril) for 3 months after surgery for chronic subdural hematoma will decrease the risc o...
Detailed Description
Previous studies have indicated that treatment with ACE inhibitors can reduce the risk of recurrence of CSDH after surgical evacuation. This randomized clinical trial was designed to investigate this
Eligibility Criteria
Inclusion
- Patients with chronic subdural hematoma that needs surgical evacuation
- Age \> 18 year
Exclusion
- Lack of compliance
- Kidney artery stenosis
- Stenosis of the aorta
- Severely decreased kidney function
- Allergy or intolerance/contraindications toward ACE inhibitors
- Already in ACE inhibitor treatment
- Coagulopathies
- Malignant disorders
- Fertile women
- Other neurological disorders
- Treatment with pharmaceuticals contraindicating treatment with ACE inhibitors
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT00915928
Start Date
July 1 2009
End Date
June 1 2012
Last Update
August 19 2020
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