Status:
COMPLETED
Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone
Lead Sponsor:
Xiao-Ming Mao
Conditions:
Graves' Disease
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Antithyroid drugs are widely used in treatment of Graves' disease (GD), but after therapy withdrawal, relapse rate is very high. The aim this trail is to evaluate the effects of intrathyroid injection...
Detailed Description
The morbility of GD is nearly 0.5% and the underlying cause of 50 to 80% of cases of hyperthyroidism.Recently,anti-thyroid drugs are still the main therapy for Graves'hyperthyroidism in a lot of distr...
Eligibility Criteria
Inclusion
- Newly diagnosed of Graves' Disease
Exclusion
- Pregnancy
- Allergy to ATD, Alanine aminotransferase (ALT) or asparate aminotransferase (AST) above 2 times of upper normal range
- Non-compliance because of psychiatric or other serious diseases, or unwillingness to participate in the study.
Key Trial Info
Start Date :
June 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
218 Patients enrolled
Trial Details
Trial ID
NCT00917241
Start Date
June 1 2004
End Date
March 1 2009
Last Update
May 6 2013
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