Status:

COMPLETED

Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in Parkinson's Disease (PD) Without Dementia

Lead Sponsor:

Washington University School of Medicine

Conditions:

Parkinson's Disease

Eligibility:

All Genders

40-70 years

Brief Summary

The overall purpose of this research is to learn how Parkinson's disease affects thinking and memory in everyday life. Participation will involve thinking tests, questionnaires and interviews about th...

Detailed Description

The overall purpose of this research is to learn how Parkinson's disease affects thinking and memory in everyday life. Participation will involve thinking tests, questionnaires and interviews about th...

Eligibility Criteria

Inclusion

  • Inclusion Criteria PD participants:
  • WUSM Movement Disorders Clinic patients
  • males or females between 40 and 70
  • meet criteria for idiopathic typical PD
  • classified at Hoehn \& Yahr12 stage I, II, or III
  • are currently treated with levodopa/carbidopa
  • Inclusion Criteria Control:
  • The groups will be matched for age, education and gender
  • No Parkinson Disease
  • Exclusion Criteria PD participants and Control:
  • suspected dementia
  • treatment with certain dopaminergic, anticholinergic or benzodiazepine medications
  • other neurological problems
  • brain surgery
  • history or current psychotic disorder
  • any condition which would interfere with testing
  • control only: a biological family history of PD and being a caregiver or spouse of someone who has PD

Exclusion

    Key Trial Info

    Start Date :

    December 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2014

    Estimated Enrollment :

    174 Patients enrolled

    Trial Details

    Trial ID

    NCT00917280

    Start Date

    December 1 2008

    End Date

    July 1 2014

    Last Update

    June 3 2015

    Active Locations (1)

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    Washington University School of Medicine

    St Louis, Missouri, United States, 63110