Status:
COMPLETED
Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Osteoarthritis Pain
Eligibility:
MALE
18-45 years
Phase:
PHASE1
Brief Summary
This study will evaluate ATP-induced Pain (AIP) and ATP-induced dermal vasodilation (AIDV) as target engagement tools for future development of analgesics.
Eligibility Criteria
Inclusion
- Subject is in generally good health
- Subject is willing to abstain from smoking within 24 hours of each iontophoresis treatment and limit smoking to 5 or less cigarettes per week during the study
Exclusion
- Subject has a history of dermatitis, psoriasis, or eczema
- Subject has active asthma and/or hay fever at the time of the screening visit
- Subject is unable to refrain from use of analgesics within 3 days prior to each treatment period
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT00917696
Start Date
October 1 2009
End Date
June 1 2011
Last Update
July 30 2015
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