Status:
COMPLETED
AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations
Lead Sponsor:
AstraZeneca
Conditions:
Healthy
Postmenopausal
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
The primary objective is to investigate the pharmacokinetics of AZD1981 given in different formulations and to measure renal clearance
Eligibility Criteria
Inclusion
- Provision of informed consent prior to any study specific procedures
- Men or post-menopausal or surgically sterile women, aged 18 to 55 years
- Have a body mass index between 19 and 30 kg/m2 and weigh at least 50 kg and no more than 100 kg
- Be a non-smoker or ex-smoker who has stopped smoking for \>6 months prior to Visit 1 (pre-entry)
Exclusion
- Any clinically significant disease or disorder which, in the opinion of the investigator, may either put the subject at risk because of participation in the study, or influence the result of the study, or the subject´s ability to participate
- Any clinically relevant abnormal findings in phys.examination, clinical chemistry, haematology, urinalysis, vital signs, or ECG at baseline which, in the opinion of the investigator, may put the subject at risk because of his participation in the study
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2009
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT00918398
Start Date
June 1 2009
End Date
July 1 2009
Last Update
July 30 2009
Active Locations (1)
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1
Research Site
Uppsala, Sweden