Status:
TERMINATED
Reversal of Ketamine Pharmacodynamic Effects With Naloxone
Lead Sponsor:
Ullevaal University Hospital
Collaborating Sponsors:
University of Oslo
Conditions:
Pain
Eligibility:
FEMALE
18-30 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether the analgetic and other effects effect of ketamine are partly mediated through opioid receptors
Detailed Description
Ketamine er et dissociative anaesthetic closely related with phencyclidine (PCP). Phencyclidine is a non-competitive NMDA-antagonist, and it is assumed that the pharmacodynamic mechanism of action for...
Eligibility Criteria
Inclusion
- Females of norwegian Caucasian origin who needs surgical removal of impacted third molars
Exclusion
- Anamnestic information regarding psychiatric diagnosis regarding mother/father or brother/sister Concommitant medication other than oral contraceptives Hypersensitivity towards NSAID/opioids/study drugs Females with suspected or confirmed pregnancy Lactating females Surgery lasting more than 60 minutes
Key Trial Info
Start Date :
December 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT00921765
Start Date
December 1 2009
End Date
December 1 2017
Last Update
April 5 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ullevaal University Hospital
Oslo, Norway, NO-0407