Status:
COMPLETED
Metformin in Overweight Type 2 Diabetes Mellitus
Lead Sponsor:
Era's Lucknow Medical College
Conditions:
Obesity
Type 2 Diabetes Mellitus
Eligibility:
All Genders
30-70 years
Phase:
NA
Brief Summary
The study included 102 overweight type 2 diabetes mellitus patients with a body mass index (BMI) of more than 25 in an open label study. They were advised intensive life style modification which was r...
Detailed Description
From 1st February 2006 till 31st December 2008, 800 cases of diabetes mellitus who attended the diabetes clinic constituted the subjects for the present study. Majority of the subjects were from the s...
Eligibility Criteria
Inclusion
- Type 2 Diabetes Mellitus
- BMI more than 25
Exclusion
- Type 1 diabetes
- pancreatic diabetes
- presence of concomitant endocrinal disorder
- non-overweight type 2 diabetes
- type 2 diabetes with secondary failure to sulfonylurea and taking insulin
- presence of proliferative retinopathy or chronic renal failure
- known cirrhosis of liver
- heavy alcoholic
- presence of active tuberculosis
- known HIV disease or any active infection
- major mental illness
- failure to comply with the exercise advice due to physical incapacity (e.g., severe osteoarthritis, hemiparesis or any other disabling neurological disease)
- present pregnancy (or planning pregnancy)
- lactating mothers
- using any kind of hormones including oral contraceptives, systemic corticosteroids, nicotinic acid
- use of anti-obesity drug within the past 3 months
- chronic gastroparesis or chronic severe gastrointestinal symptoms
- a history of gastric or duodenal ulcers
- abdominal surgery within 1 year will not be included in the study
- patients with congestive heart failure or overt nephropathy will also not be included, due to unreliability of anthropometric measurements in such subjects and the relative risk of lactic acidosis
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT00922194
Start Date
February 1 2006
End Date
December 1 2008
Last Update
March 23 2010
Active Locations (1)
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1
Sircar Diabetes Clinic
Lucknow, Uttar Pradesh, India, 226006