Status:

COMPLETED

Renal HYPODYSPLASIA : Genetic and Familial Assessment

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

URC-CIC Paris Descartes Necker Cochin

Conditions:

Renal HYPODYSPLASIA, Nonsyndromic, 1

Eligibility:

All Genders

3-18 years

Brief Summary

Evaluation of the frequency of familial cases of renal HYPODYSPLASIA

Detailed Description

DNA collection from the propositus and its family. A questionnaire will be filled by the parents to seek other affected individual in the family.With another affected member, DNA collection will be co...

Eligibility Criteria

Inclusion

  • Inclusion criteria :
  • \- Children aged more than 3 months and less than 18 years old with a renal bilateral HYPODYSPLASIA set by renal ultrasound examination :
  • renal size \< -2DS
  • with/or hyperechogenicity or lack of cortical-medullary differentiation
  • with/or renal cysts
  • Exclusion criteria :
  • Bladder uropathy or sus-bladder uropathy
  • Recessive or dominant renal polycystic disease
  • Bardet-Biedl syndrome and other malformative syndromes except renal coloboma syndrome, Renal cysts and diabetes syndrome RCAD
  • Lack of written informed consent

Exclusion

    Key Trial Info

    Start Date :

    April 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2014

    Estimated Enrollment :

    342 Patients enrolled

    Trial Details

    Trial ID

    NCT00925379

    Start Date

    April 1 2009

    End Date

    July 1 2014

    Last Update

    November 20 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Necker Hospital

    Paris, France, 75015