Status:
COMPLETED
Liver Transplantation and Reticuloendothelial Clearance Capacity
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
NHS Lothian
European Society of Organ Transplantation
Conditions:
Hepatic Insufficiency
Liver Insufficiency
Eligibility:
All Genders
18-80 years
Brief Summary
Study summary: "Liver transplantation and the reticuloendothelial clearance capacity." The purpose of this study is to evaluate the effect of liver transplantation on the immune system. This study w...
Detailed Description
Introduction Liver cells called hepatocytes undertake the most important metabolic functions of the liver. The liver also contains a large number of immune cells called Kupffer cells. These cells act...
Eligibility Criteria
Inclusion
- written informed consent
- chronic liver disease
- listed for transplantation at the Scottish Liver Transplant Unit
Exclusion
- pregnancy (although pregnant patients would not be listed for liver transplant)
- prisoners
- acute liver failure
- living-related liver transplantation
- multi-organ transplantation or re-transplantation
- ABO incompatible donor
- HIV-positive donor or recipient
- not given informed consent
Key Trial Info
Start Date :
September 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2010
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00929032
Start Date
September 1 2009
End Date
August 1 2010
Last Update
October 20 2010
Active Locations (1)
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1
University of Edinburgh
Edinburgh, Midlothian, United Kingdom, EH16 4TJ