Status:
COMPLETED
Exercise Program in Women With Metabolic Syndrome
Lead Sponsor:
Beth Israel Deaconess Medical Center
Conditions:
Metabolic Syndrome
Eligibility:
FEMALE
50+ years
Phase:
NA
Brief Summary
The purpose of this study is to test whether a supervised mixed aerobic and strength training (MAST) program is effective in improving overall physical fitness and blood flow in the brain and lowering...
Detailed Description
Metabolic syndrome is a cluster of conditions and disorders that increase the risk for coronary artery disease (CAD) and strokes. Sedentary lifestyle is one of the risk factors, which decrease overall...
Eligibility Criteria
Inclusion
- Post-menopausal women
- Age 50 or over
- Diagnosed metabolic syndrome
Exclusion
- Any unstable or acute medical condition that the study physician deem unsafe for participation
- Positive stress test for CAD or other ischemic conditions
- Myocardial infarction or major surgery within 6 months
- History of a clinically documented stroke
- Clinical dementia (by history) or inability to follow details of the protocol
- Carotid stenosis \> 50% by medical history
- Insulin dependent diabetes mellitus (also type II, if using insulin) or history of severe hypoglycemic episodes within 6 months requiring hospitalization
- Liver or renal failure or transplant
- Severe blood pressure elevation (systolic BP \> 180 and/or diastolic BP \> 110 mm Hg)
- Anemia (Hb \< 10)
- Seizure disorders
- Current recreational drug or alcohol abuse
- BMI \> 45, but body weight under 280 lbs
- Inability to obtain permission for participation from the primary care physician
- Clinically significant and movement limiting hip, knee and/or back disorders or injury, and rheumatoid arthritis
- Transcranial Doppler (TCD) exclusion criteria - poor insonation window and TCD signal
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT00929500
Start Date
July 1 2009
End Date
December 1 2013
Last Update
November 13 2017
Active Locations (1)
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1
Beth Israel Deaconess Medical Center, Harvard University
Boston, Massachusetts, United States, 02215