Status:
UNKNOWN
Transient Lower Esophageal Sphincter Relaxations and High Resolution Manometry
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Transient lower esophageal sphincter relaxations (tLESr) are the main mechanism of gastro-oesophageal reflux disease. They occur without any deglutition in patients but also in healthy volunteers. The...
Eligibility Criteria
Inclusion
- Male or Female between 18 and 60 years
- Subject without typical or atypical symptoms of gastro-esophageal reflux disease (heartburn, regurgitation, epigastric pain, chest pain, chronic cough, pharyngeal pain)
- Subject without any medication (except oral contraception)
- Subject without previous digestive surgery history (except appendicectomy)
- Capability to pass manometric probes through each nostril
- Subject with health insurance
- Written informed consent
- No participation to another study at the same time
Exclusion
- Age under 18 years or upper 60
- Pregnant woman or lactation
- Incapability to give consent
- No written informed consent
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00931593
Start Date
May 1 2009
End Date
December 1 2009
Last Update
July 2 2009
Active Locations (3)
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1
Hôpital St André, CHU BORDEAUX
Bordeaux, France, 33075
2
Hôpital Edouard Herriot - Hospices Civils de Lyon
Lyon, France, 69437
3
Hôpital Hôtel Dieu, CHU NANTES
Nantes, France, 44093