Status:
COMPLETED
Effects of Ultrasound Therapy on Cartilage Healing in Patients With Knee Osteoarthritis
Lead Sponsor:
McMaster University
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
45+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine the effects of low intensity ultrasound therapy over the cartilage morphology (thickness and volume) of patients with mild or moderate knee osteoarthritis.
Detailed Description
Knee osteoarthritis (OA) negatively influences the healthy aging process of the population. Until today, there are no interventions that have proved effective for enhancing the cartilage regeneration ...
Eligibility Criteria
Inclusion
- Adults ≥ 45 years old.
- Fulfillment of the clinical / radiological diagnostic criteria proposed by Altman, et al. for knee osteoarthritis.
- Medial Tibiofemoral Compartment joint space narrowing grades 1 OR 2 according to the OARSI atlas guide.
- Ability to read and understand English questionnaires and follow instructions.
Exclusion
- Presence of Metabolic related arthritis (calcium crystal deposition, hemochromatosis, acromegaly)
- Arthritis related to trauma (major joint trauma, joint surgery)
- Presence of inflammatory disorders (rheumatoid arthritis, ankylosing spondylitis, septic arthritis)
- Previous surgical knee intervention
- Intraarticular injection of the knee in the previous 6 months.
- Presence of an unexpected traumatic episode in the affected knee (s) during the course of the study.
- Any contraindication for X ray or peripheral MRI study.
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT00931749
Start Date
September 1 2009
End Date
June 1 2010
Last Update
June 9 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
School of Rehabilitation Science, Institute of Applied Health Sciences, McMaster University
Hamilton, Ontario, Canada, L8S 4L8