Status:

TERMINATED

Oculomotor and Spatial Cognition Deficits in Schizophrenia

Lead Sponsor:

University of Illinois at Chicago

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Schizophrenia

Eligibility:

All Genders

15-64 years

Phase:

NA

Brief Summary

DESCRIPTION: (Verbatim from the Applicant's Abstract) Abnormalities of eye movement control and spatial cognition are well-established deficits in schizophrenia. However, the regional disturbances in ...

Detailed Description

We will be assessing clinical symptoms and cognition before and after treatment.

Eligibility Criteria

Inclusion

  • Inclusion criteria for this study are (1) able and willing to give written informed consent; (2) no contraindications to MRI (cardiac pacemaker, aneurysm clip, cochlear implants, IUD, shrapnel, history of metal fragments in eyes, neurostimulators or other metal devices, weight of 250lbs or more, claustrophobia) and (3) medically stable. Sedation will not be used for MRI studies because cooperation is essential.

Exclusion

  • Any subject is excluded from the imaging studies if they have any contraindications to MRI such as cardiac pacemaker, aneurysm clip, cochlear implants, pregnancy in the later stages (because of body size and limited comfort for MRI studies), IUD, shrapnel, history of metal fragments in eyes, neurostimulators, weight of 250 lbs. or more, or claustrophobia. Individuals with mental retardation, neurologic disease or significant medical illness that might effect neuronal or vascular physiology will not be recruited.

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00931996

Start Date

June 1 2009

End Date

November 1 2011

Last Update

January 24 2013

Active Locations (1)

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UIC Center for Cognitive Medicine

Chicago, Illinois, United States, 60612