Status:

COMPLETED

S8809-S9800-S9911-S9704-A Study of Blood and Tissue Samples From Patients With Follicular Lymphoma Treated With Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone

Lead Sponsor:

SWOG Cancer Research Network

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Lymphoma

Eligibility:

All Genders

18+ years

Brief Summary

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It ma...

Detailed Description

OBJECTIVES: * To test for association of polymorphisms in Fc-gamma (Fcγ) receptors IIa (H/R131) and IIIa (V/F158) with progression-free survival and clinical response in patients with follicular non-...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of follicular lymphoma
  • Meets either of the following criteria:
  • Previously enrolled on clinical trial SW0G-8809 and treated with chemotherapy alone
  • Excess tissue sections available
  • Previously enrolled on clinical trial SWOG-9800 or SWOG-9911 and treated with a combination of chemotherapy and monoclonal antibody therapy
  • Matched serum and tissue samples available from the SWOG Lymphoma Bank
  • PATIENT CHARACTERISTICS:
  • See Disease Characteristics
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    December 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2012

    Estimated Enrollment :

    142 Patients enrolled

    Trial Details

    Trial ID

    NCT00933127

    Start Date

    December 1 2008

    End Date

    June 1 2012

    Last Update

    July 24 2014

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