Status:

RECRUITING

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Lead Sponsor:

Barbara Ann Karmanos Cancer Institute

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Brain and Central Nervous System Tumors

Chronic Myeloproliferative Disorders

Eligibility:

All Genders

18-120 years

Brief Summary

RATIONALE: Diagnostic procedures, such as 3'-deoxy-3'-\[18F\] fluorothymidine (FLT) PET imaging, may help find and diagnose cancer. It may also help doctors predict a patient's response to treatment a...

Detailed Description

OBJECTIVES: Primary * Evaluate the use of 3'-deoxy-3'-\[18F\] fluorothymidine (FLT) positron emission tomography (PET) imaging to measure tumor proliferation and the DNA synthetic pathway (thymidine...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Meets one of the following criteria:
  • Histologically confirmed solid tumor or hematologic malignancy
  • Awaiting biopsy or surgery for cancer evaluation of a mass detected on exam or standard imaging
  • PATIENT CHARACTERISTICS:
  • Able to lie still in the PET scanner
  • Girth and weight must be suitable to enter the gantry
  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    September 1 2009

    Trial Type :

    INTERVENTIONAL

    End Date :

    May 1 2028

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT00935090

    Start Date

    September 1 2009

    End Date

    May 1 2028

    Last Update

    July 8 2025

    Active Locations (1)

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    Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, United States, 48201-1379