Status:
UNKNOWN
Development of Escitalopram Genomic Device by Using Candidate Gene Approach and Genome-Wide Scanning
Lead Sponsor:
Samsung Medical Center
Collaborating Sponsors:
H. Lundbeck A/S
Conditions:
Depression
Continuous Antidepressant Abuse
Eligibility:
All Genders
19-89 years
Phase:
NA
Brief Summary
To reveal the genetic determinants of the treatment outcome of escitalopram in depressed patients (by using candidate gene approach and whole genome scanning).
Detailed Description
The purposes of this study are: 1. To reveal the genetic determinants of the treatment outcome of escitalopram in depressed patients (by using candidate gene approach and whole genome scanning) 2. To...
Eligibility Criteria
Inclusion
- Eligible patients were enrolled in the clinical trials program of hte Samsung Medical Center Geropsychiatry and Affective Disorder Clinics(Seoul, Korea). They received a semistructured diagnostic interview, the Samsung Psychiatric Evaluation Schedule. The affective disorder section of the Samsung Psychiatric Evaluation Schedule uses the Korean version of the structured clinical interview for the diagnostic and statistical manual of mental disorders, Fourth edition.
- interview with one more patient's family member for objective diagnosis and final diagnosis decision by agreements of two more psychiatric physicians
Exclusion
- received psychotropic medication within 2 weeks of the study or fluoxetine within 4 weeks
- potential study participants for pregnancy, significant medical conditions, abnormal laboratory baseline values, unstable psychiatric features(eg.suicidal), history of alcohol of drug dependence, seizures, head trauma with loss of consciousness, neurological illness, or concomitant Axis I psychiatric disorder.
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2016
Estimated Enrollment :
202 Patients enrolled
Trial Details
Trial ID
NCT00935246
Start Date
December 1 2008
End Date
December 1 2016
Last Update
December 31 2015
Active Locations (1)
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1
Samsung Medical Center
Kangnam, Seoul, South Korea, 135-710