Status:
COMPLETED
Study of Bone Disease in Older HIV-infected Adults
Lead Sponsor:
Ruth M. Rothstein CORE Center
Collaborating Sponsors:
Rush University Medical Center
Merck Sharp & Dohme LLC
Conditions:
Osteopenia
Osteoporosis
Eligibility:
All Genders
50-70 years
Brief Summary
This study will look to see if there are changes in the blood cells that are associated with bone disease and sort out effects that are due to the HIV virus itself, the medications and see if faster a...
Eligibility Criteria
Inclusion
- HIV-1 infection documented by ELISA and confirmed by western blot
- Treatment with antiretroviral drugs for at least 12 months
- Age 50-70 years
- CD4 count \> 350 cells/mm3 for at least 6 months
- HIV-RNA undetectable (\< 75 copies/ml for at least 6 months)
Exclusion
- Known bone disease (primary or metastatic malignancy, osteomalacia)
- Treatment for bone disease (bisphosphonates, calcitonin, strontium, sodium fluoride, synthetic PTH, or high-dose vitamin D \[\> 800 IU daily\]).
Key Trial Info
Start Date :
December 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
101 Patients enrolled
Trial Details
Trial ID
NCT00935935
Start Date
December 1 2009
End Date
February 1 2011
Last Update
August 3 2012
Active Locations (1)
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1
Ruth M Rothstein CORE Center
Chicago, Illinois, United States, 60612