Status:

COMPLETED

Effects of Unloading on Muscle Mass

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Immobilization

Physical Inactivity

Eligibility:

MALE

18-35 years

Phase:

NA

Brief Summary

In the present study, the effects of 3 weeks of unloading on muscle mass and muscle fiber characteristics will be determined. In addition, the effects of 6 weeks of recovery will be assessed.

Eligibility Criteria

Inclusion

  • Healthy
  • BMI \< 30 kg/m2

Exclusion

  • Use of medication that may affect haemostasis
  • Subjects with (recent) musculoskeletal/orthopaedic disorders known to affect the outcome of the study or that compromise their ability to walk with crutches
  • Subjects with metal implants in their lower limbs
  • Subjects with known cardiovascular and/or haemostasis disorders
  • Subjects with known severe hypertension

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2013

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00936039

Start Date

October 1 2009

End Date

June 1 2013

Last Update

July 2 2013

Active Locations (1)

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Maastricht University Medical Centre

Maastricht, Netherlands, 6200MD