Status:

COMPLETED

TS Gene Polymorphism Predicts Effect in Patients With Advanced Lung Cancer

Lead Sponsor:

Hunan Province Tumor Hospital

Conditions:

Non-small-cell Lung Cancer

Adenocarcinoma

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

The investigators performed a multicenter, open trial of using TS gene polymorphism to predict advanced lung adenocarcinoma effect to pemetrexed combined with cisplatin regiment as first-line treatmen...

Detailed Description

1. Main eligibility criteria were histologic or cytologic proof of advanced non-small-cell lung cancer (NSCLC) primary treatment, normal organ function, and Eastern Cooperative Oncology Group performa...

Eligibility Criteria

Inclusion

  • histologic or cytologic proof of advanced lung adenocarcinoma
  • primary treatment
  • normal organ function
  • Eastern Cooperative Oncology Group performance status 0 to 2

Exclusion

  • Symptomatic patients with brain metastases
  • Major organ dysfunction and severe heart disease

Key Trial Info

Start Date :

March 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2015

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00940069

Start Date

March 1 2009

End Date

January 1 2015

Last Update

February 22 2016

Active Locations (1)

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HuNan province tumor hospital

Changsha, Hunan, China, 410013