Status:
COMPLETED
Vitamin D3 Supplementation and the T Cell Compartment in Multiple Sclerosis (MS)
Lead Sponsor:
Maastricht University Medical Center
Collaborating Sponsors:
Orbis Medical Centre
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In patients with Relapsing Remitting Multiple Sclerosis (RRMS), the investigators observed a positive correlation between regulatory T cell (Treg) function and vitamin D status. The present goal is to...
Detailed Description
In several studies, Multiple Sclerosis (MS) incidence and disease activity has been related with vitamin D status. We observed that RRMS patients who remained relapse free before blood collection had ...
Eligibility Criteria
Inclusion
- Relapsing Remitting MS (Revised MCDonald criteria 2005)
- Age \> 18 years
Exclusion
- Progressive MS phenotype
- Abnormalities of vitamin D hormonal system other than low dietary intake or limited sun exposure
- Intake of drugs that influence vitamin D homeostasis other than corticosteroids
- Conditions with in increased susceptibility to hypercalcemia
- Alcohol or drug abuse
- Pregnancy or the intention to become pregnant within the study period
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2010
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00940719
Start Date
August 1 2009
End Date
July 1 2010
Last Update
August 11 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Orbis Medical Center
Sittard, Netherlands, 6130MD