Status:
COMPLETED
Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS)
Lead Sponsor:
University of Thessaly
Collaborating Sponsors:
Center for Research and Technology Thessaly - CERETETH
European Social Fund
Conditions:
Restless Legs Syndrome
End Stage Renal Disease
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Uremic etiology Restless legs syndrome (RLS) has been associated with poorer quality of life (QoL) compared to RLS-free counterparts mainly due to sleep deprivation factors. Exercise training in hemod...
Detailed Description
This is a randomized, placebo-controlled study to evaluate the acute and long term (6 months) effect of exercise training in combination with dopamine agonists in quality of life, muscle function, sle...
Eligibility Criteria
Inclusion
- Clinically stable hemodialysis patients with positive diagnosis in IRLSS questionnaire for the RLS will be eligible to participate. Entry criteria included being on chronic hemodialysis for six months, able to perform an exercise training, with dialysis delivery (KT/V) \> 1.1.
Exclusion
- Patients were excluded from the study if they were diagnosed with neuropathies or reasons for being in a catabolic state (including malignancies, HIV and opportunistic infections, active inflammation), within 3 months prior to the start of the study. In addition patients treated with drugs recommended for the treatment of RLS as well as patients with Parkinson's disease or untreated depression will be also excluded.
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2010
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT00942253
Start Date
September 1 2006
End Date
July 1 2010
Last Update
July 5 2010
Active Locations (1)
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1
University Hospital of Larissa, Nephrology Clinic
Larissa, Thessaly, Greece, 41110