Status:
COMPLETED
The Effects of Dietary Intervention on Gastrointestinal Function in Patients With Anorexia Nervosa and Obesity
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
Schweizerischer Nationalfonds
Conditions:
Anorexia Nervosa
Obesity
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Diseases characterized by abnormal low and high body weight are common in the community and are associated with significant morbidity, mortality and health care related costs. Genetic, dietary, socia...
Eligibility Criteria
Inclusion
- In addition to satisfying specific DSMIV criteria for anorexia nervosa (B1, B2) or WHO criteria for obesity (C1), or obesity and diabetes mellitus type II (C2), general inclusion criteria include:
- aged at least 18 and not more than 40 years
- able to communicate well with the investigators and provide written consent
- no physical co-morbidity requiring active treatment, in particular diabetes mellitus, impairment of liver or kidney function (subjects with diabetes mellitus type II are eligible for study group C2)
- no psychiatric (DSM IV) disorders limiting the ability to comply with study requirements
- no use of medications influencing upper GI motility within one week of the study (i.e. nitrates, prokinetic drugs, macrolide antibiotics). Acid suppression and antihypertensive medication beta-blocker, calcium channel blockers are acceptable.
- no evidence of current drug or alcohol abuse
- no history of gastrointestinal disease or surgery except appendicectomy or hernia repair
- females will take a urine pregnancy test before each study, any participant with a positive pregnancy test will be excluded (females will be investigated always in the same menstrual phase)
- Exclusion criteria:
- • pregnancy
Exclusion
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00946816
Start Date
September 1 2010
End Date
November 1 2012
Last Update
November 14 2012
Active Locations (1)
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1
University Hospital Zurich, Gastroenterology and Hepatology
Zurich, Canton of Zurich, Switzerland, 8091