Status:
UNKNOWN
Safety and Efficacy Study of Cylindrical Abdominoperineal Resection to Treat Rectal Cancer
Lead Sponsor:
Beijing Chao Yang Hospital
Collaborating Sponsors:
Shandong Provincial Hospital
Shandong Cancer Hospital and Institute
Conditions:
Rectal Cancer
Treatment
Eligibility:
All Genders
18-80 years
Brief Summary
The purpose of this study is to determine whether cylindrical abdominoperineal resection is effective in the treatment of advanced very low rectal cancer
Detailed Description
Abdominoperineal resection (APR) is still a common operation in patients with tumours less than 6 cm from the anal verge. The perineal phase of APR is a difficult part of the operation, often done wit...
Eligibility Criteria
Inclusion
- Tumor within 6 cm of the anal verge, or with very narrow pelvis
- T3-T4 as determined by preoperative MRI or endorectal ultrasonography examination, or a low tumor is fixed or tethered at rectal examination
- Absence of distant metastases
- Absence of intestinal obstruction
Exclusion
- T1-T2 as determined by preoperative MRI or endorectal ultrasonography examination
- with distant metastases
- with intestinal obstruction
- pregnancy or lactation
- allergic constitution to heterogeneous protein
- with operation contraindication
- with mental disorder
Key Trial Info
Start Date :
July 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2013
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00949273
Start Date
July 1 2009
End Date
November 1 2013
Last Update
November 28 2013
Active Locations (7)
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1
Beijing Luhe Hospital
Beijing, Beijing Municipality, China, 100000
2
General Surgery, Beijing Chao Yang Hospital
Beijing, Beijing Municipality, China, 100020
3
The first Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China, 450003
4
Zhongnan Hospital, Wuhan University
Wuhan, Hubei, China, 430077