Status:
TERMINATED
Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy
Lead Sponsor:
Loma Linda University
Conditions:
Postoperative Pain
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Purpose: To compare the efficacy of oral gabapentin and its newer analogue pregabalin in postoperative pain control after photorefractive keratectomy (PRK). Methods: One hundred and four patients who...
Detailed Description
METHODS: One hundred and four patients who meet the inclusion criteria undergoing photorefractive keratectomy (PRK) in one or both eyes will be randomly assigned into one of two treatment groups via ...
Eligibility Criteria
Inclusion
- 18 years of age or older
- Undergoing PRK in at least one eye
Exclusion
- Serious medical problems within the last 6 months including myocardial infarction (heart attack), congestive heart failure, stroke, deep vein thrombosis, pulmonary embolism, and other conditions, etc.
- Serious kidney disease as evidenced by the need for dialysis or kidney transplant.
- History of seizure or other neurologic disorders.
- Patients intending to become pregnant or who are pregnant or nursing over the projected course of treatment.
- Currently taking gabapentin or pregabalin for other medical purposes.
- Known allergic reaction to gabapentin or pregabalin from previous use.
- Plans to move out of the area within 8 weeks after the surgery.
Key Trial Info
Start Date :
November 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00954187
Start Date
November 1 2009
End Date
April 1 2013
Last Update
January 9 2017
Active Locations (1)
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1
Loma Linda University - Ophthalmology
Loma Linda, California, United States, 92354