Status:
COMPLETED
Identification and Treatment Response Prediction of Antipsychotic-Related Metabolic Syndrome
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
Yu-Li Veterans Hospital
Yu-Li Hospital
Conditions:
Metabolic Syndrome X
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
The investigators developed an easy identification model to identify metabolic syndrome in patients with schizophrenia or schizoaffective disorder who received treatment of clozapine, olanzapine, or r...
Eligibility Criteria
Inclusion
- Stage I for identification of metabolic syndrome:
- A diagnosis of schizophrenia, schizoaffective disorder, delusional disorder, mood disorders, or anxiety disorders based on DSM-IV-TR criteria.
- Age at least 20 years old.
- The current antipsychotic drugs have been used for at least 3 months before evaluation.
- Psychiatrically stable with Clinical Global Impression of Severity scale (CGI-S) not greater than 5
Exclusion
- Severe uncontrolled medical illnesses, including cardiovascular, hepatic, renal and metabolic diseases (eg. cancer, poor-control hypertension, diabetes mellitus, and other metabolic diseases).
- Organic mental or neurological disorder, substance abuse or dependence (alcohol, amphetamine, heroin).
- Pregnant or breast-feeding women.
- Patients from Yuli Veterans Hospital, who attended our previous study of identification model.
- Stage II for switch response:
- Inclusion Criteria:
- The same as Stage I criteria.
- Fulfill the metabolic syndrome criteria.
Key Trial Info
Start Date :
November 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2012
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT00956189
Start Date
November 1 2009
End Date
October 1 2012
Last Update
January 3 2013
Active Locations (3)
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1
Yu-Li Hospital
Yuli, Hualien County, Taiwan, 981
2
Yu-Li Veterans Hospital
Yuli, Hualien County, Taiwan, 981
3
National Taiwan University Hospital
Taipei, Taiwan, 10002