Status:
COMPLETED
Comparison of Low Fat and Low Carbohydrate Diets With Respect to Weight Loss and Metabolic Effects
Lead Sponsor:
Hannover Medical School
Conditions:
Obesity
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The investigators will test the hypothesis that a LOW CARB hypocaloric diet will reduce body weight over six months more than a LOW FAT hypocaloric diet. In addition to body weight, the investigators ...
Eligibility Criteria
Inclusion
- Body Mass Index \> 27 kg/m2
- No chronic medication (except oral contraceptives and L-Thyroxine) or possibility to stop medication for study duration
- Able to give written informed consent
Exclusion
- Pregnancy and nursing
- Severe cardiovascular, liver, kidney, hepatic or orthopedic disease that need treatment
- Metabolic or endocrine disease that need treatment
- Hypertension blood pressure \> 160/95 mmHg or need of \> 2 drugs
- Previous stroke or cerebral ischemia
- Significant neurologic or psychiatric disease
- Any kind of eating disorder
- Bariatric surgery in the past
- Drug or alcohol abuse
- Any cancer in the past
- Acute and chronic infections
- Metallic implants (e.g. pace makers) or conditions that do not allow MRI scans
- Body weight \> 130 kg
Key Trial Info
Start Date :
April 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
170 Patients enrolled
Trial Details
Trial ID
NCT00956566
Start Date
April 1 2007
End Date
July 1 2012
Last Update
July 30 2012
Active Locations (1)
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1
Experimental & Clinical Research Center
Berlin, Germany, 13125