Status:

TERMINATED

Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy

Lead Sponsor:

Johns Hopkins University

Conditions:

Prostate Cancer

Eligibility:

MALE

35-75 years

Phase:

EARLY_PHASE1

Brief Summary

A new solution for guiding the surgeon in robot-assisted laparoscopic radical prostatectomy (RALP) is image-guided navigation using transrectal ultrasound (TRUS). A TRUS-guided intraoperative navigati...

Detailed Description

The preservation of the neurovascular bundle (NVB) including cavernous nerves during radical prostatectomy improves the postoperative recovery of sexual potency. At present, the location of NVB is det...

Eligibility Criteria

Inclusion

  • Patients must be scheduled for a robotic LRP
  • Patients must be between the ages of 35 and 75
  • Patients must not have one of the listed exclusion criteria
  • Patients must be able to understand and willing to adhere to the study protocol
  • Patients must have a clinical stage diagnosis of T1 or T2
  • Patients must have a preoperative serum PSA \< 20ng/ml
  • Patients must have a biopsy Gleason score of 5-8

Exclusion

  • Patients less than 35 years of age and over 75 years of age.
  • Patients with previous rectal surgery
  • Patients with anal stenosis that prevents the TRUS probe insertion
  • Patients with extensive abdominal surgery
  • Patients with inadequate bowel prep
  • Patients who are unwilling or unable to sign informed consent
  • Patients on anticoagulation medication (eg. coumadin, lovenox, or heparin)
  • Patients with a clinical stage diagnosis of T3 - Patients with a preoperative serum PSA ≥ 20 ng/mL
  • Patients with a biopsy Gleason score \< 5 or \> 8

Key Trial Info

Start Date :

August 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2013

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00956904

Start Date

August 1 2009

End Date

June 1 2013

Last Update

June 19 2013

Active Locations (1)

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1

Johns Hopkins Hospital

Baltimore, Maryland, United States, 21287