Status:
TERMINATED
Positron Emission Tomography and Computed Tomography in Planning Treatment for Patients Undergoing 3-Dimensional Conformal Radiation Therapy for Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery. ICORG 06-35
Lead Sponsor:
Cancer Trials Ireland
Conditions:
Lung Cancer
Metastatic Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
RATIONALE: Diagnostic procedures, such as positron emission tomography and computed tomography, may help learn the extent of disease and allow doctors to plan 3-dimensional conformal radiation therapy...
Detailed Description
Pilot Study- Primary Objectives: * Prospective evaluation of the technical feasibility of integrating PET-CT fusion in St Luke's Hospital * Rate of PET-CT Scan based treatment delivery Pilot Study- ...
Eligibility Criteria
Inclusion
- Histologically proven (biopsy or cytology) NSCLC (SCC, Adenocarcinoma, Large Cell)
- TNM clinical non-operable stage I/II and non-resectable stage IIIa/b without pleural effusion
- Measurable disease
- No other malignancy, except non-melanomatous skin cancer, within 5 years prior to participation in this study; the disease-free interval from any prior carcinoma must be continuous
- Patient suitable for radical 3-DCRT
- ECOG-Performance status ≤ 2 / KPS \> or equal to 60
- Weight loss \<10% within the 3 months prior to diagnosis
- No prior radiotherapy to the thorax
- Patient is suitable for lung-board immobilisation
- No chemotherapy received prior to planning PET-CT scan
- Age 18 and over
- Provision of written informed consent
Exclusion
- Evidence of any other significant clinical disorder or laboratory finding that makes it undesirable for the patient to participate in the trial or if it is felt by the research / medical team that the patient may not be able to comply with the protocol.
- FEV1 \< 1
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00958321
Start Date
March 1 2007
Last Update
May 24 2017
Active Locations (1)
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1
St Luke's Radiation Oncology Network
Dublin, Ireland, 6