Status:

COMPLETED

The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Pemphigus

Auto-immune Thrombocytopenic Purpura

Eligibility:

All Genders

18+ years

Brief Summary

The primary purpose of the study is to describe by a prospective observational study the serious adverse events occurring in patients treated off-label by rituximab for various auto-immune diseases.

Detailed Description

Every patient treated by rituximab off -label for auto-immune diseases in the public hospitals of the Midi-Pyrénées County (France) is eligible for the study, whatever the dose and the number of plann...

Eligibility Criteria

Inclusion

  • Age over 18 years
  • rituximab is prescribed off-label for an auto-immune disorder
  • rituximab prescription is validated by an institutional board
  • Patients have given their informed consent to be included in the cohort

Exclusion

  • Follow-up for 6 months presumably doubtful
  • Rituximab is prescribed for rheumatoïd arthritis
  • Rituximab is prescribed for lymphoma
  • Pregnant or breath feeding women

Key Trial Info

Start Date :

June 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2012

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT00960713

Start Date

June 1 2009

End Date

January 1 2012

Last Update

October 23 2012

Active Locations (1)

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1

Service de médecine interne, hôpital Purpan, place du Dr Baylac

Toulouse, France, 31059