Status:
WITHDRAWN
Characterizing Knee Pain and Response to Surgery Using Local Biomarkers
Lead Sponsor:
Stanford University
Conditions:
Inflammation
Eligibility:
All Genders
18-90 years
Brief Summary
The diagnosis and monitoring of clinically-significant pathologies of the knee remains challenging, and it is unknown why only some injuries become painful or respond to surgical intervention. The lim...
Detailed Description
Lavage of the operative and contralateral knee for comparison are performed under anesthesia prior to arthroscopy by the infusion of 10cc sterile saline into the knee joint followed by the immediate w...
Eligibility Criteria
Inclusion
- •Adult patients with knee pain (acute or chronic) who had failed conservative treatment and elected for arthroscopic management. Indications for surgery included the presence of mechanical symptoms on history, a physical examination positive for McMurray's maneuver or joint line tenderness or both, absence of severe joint space narrowing on plain radiography, and the presence of grade III signal changes on MRI in an anatomic location consistent with the history and physical examination.
Exclusion
- Less than 18 years old.
- Recent (within three months) intra-articular corticosteroid injection and past or current medical history of autoimmune disease (i.e. rheumatoid arthritis).
- In addition, no patients involved in a worker's compensation claim or personal injury litigation were enrolled in the study.
Key Trial Info
Start Date :
July 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00961623
Start Date
July 1 2009
End Date
December 1 2011
Last Update
June 4 2019
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305