Status:
ACTIVE_NOT_RECRUITING
Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
Lead Sponsor:
Alfredo Gamboa
Collaborating Sponsors:
Vanderbilt University Medical Center
Conditions:
Postural Tachycardia Syndrome
Postural Orthostatic Tachycardia Syndrome
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The investigators will test whether breathing through an inspiratory resistance device will improve the ability to be upright and decrease heart rate increases on standing in patients with postural ta...
Detailed Description
Chronic orthostatic intolerance, sometimes known as the postural tachycardia syndrome (POTS), is the most common disorder among patients seen at several centers specializing in diseases of the autonom...
Eligibility Criteria
Inclusion
- Diagnosed with postural tachycardia syndrome by the Vanderbilt Autonomic Dysfunction Center
- Increase in heart rate ≥ 30 beats/min with position change from supine to standing (10 minutes)
- Chronic symptoms consistent with POTS that are worse when upright and get better with recumbence
- Able and willing to provide informed consent
Exclusion
- Overt cause for postural tachycardia (such as acute dehydration)
- Inability to give, or withdrawal of, informed consent
- Pregnant
- Other factors which in the investigator's opinion would prevent the subject from completing the protocol
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00962728
Start Date
July 1 2009
End Date
December 1 2026
Last Update
December 22 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232