Status:
UNKNOWN
The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis
Lead Sponsor:
Tehran University of Medical Sciences
Conditions:
Atherosclerosis
Eligibility:
All Genders
35-60 years
Phase:
PHASE4
Brief Summary
The aim of this study is the comparison between the effects of supplementation with 25000 IU preformed vitamin A (retinyl palmitate) or placebo for 3 months on immune system and Th1/Th2 balance in pat...
Detailed Description
Atherosclerosis, the leading cause of death and disability in the world, is considered an inflammatory disease with a complex etiology. The immune system has a prominent role in the formation, develop...
Eligibility Criteria
Inclusion
- The criteria for enrollment of the patients and control subjects is consecutive patients of both sexes referred to the Division of Cardiology of the one of the Hospitals of Tehran University of Medical Sciences for coronary angiography for investigation of chest pain and/or suspected CAD.
Exclusion
- Patients who have diseases which affect on Th1/Th2 balance such as asthma, active viral infections, and autoimmune diseases, OR
- Patients who have allergy to vitamin A compounds, OR
- Patients who have used vitamin supplements in last 3 months.
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2013
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00963222
Start Date
September 1 2009
End Date
March 1 2013
Last Update
June 5 2012
Active Locations (1)
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1
Tehran University of Medical Sciences, School of Public Health
Tehran, Tehran Province, Iran